Department of Psychology, University of Mississippi, Oxford, MS 38677, USA.
Headache. 2010 Mar;50(3):485-8. doi: 10.1111/j.1526-4610.2009.01594.x. Epub 2009 Dec 21.
Hormonal influences associated with the female menstrual cycle play strong roles in both migraine and particular types of breast cancer, but there is limited literature on the effects of breast cancer treatment regimens in women with migraine. The present case describes resolution of menstrually related migraine following aggressive treatment for infiltrating ductal carcinoma (neoadjuvant chemotherapy, single radical mastectomy, and locoregional radiation therapy) that was maintained with supplemental treatment using tamoxifen, an anti-estrogenic agent. This novel case is presented to stimulate further research into the hormonal mechanisms underlying migraine.
与女性月经周期相关的激素影响在偏头痛和特定类型的乳腺癌中都起着重要作用,但关于偏头痛女性的乳腺癌治疗方案的影响的文献有限。本病例描述了浸润性导管癌(新辅助化疗、单一根治性乳房切除术和局部区域放射治疗)强化治疗后与月经相关的偏头痛的缓解,并用抗雌激素药物他莫昔芬进行了补充治疗。提出这个新病例是为了激发对偏头痛背后的激素机制的进一步研究。