National Evolutionary Synthesis Center, Duke University, Durham, NC, USA.
J Evol Biol. 2010 Feb;23(2):407-21. doi: 10.1111/j.1420-9101.2009.01911.x. Epub 2009 Dec 21.
The pattern of genetic variances and covariances among characters, summarized in the additive genetic variance-covariance matrix, G, determines how a population will respond to linear natural selection. However, G itself also evolves in response to selection. In particular, we expect that, over time, G will evolve correspondence with the pattern of multivariate nonlinear natural selection. In this study, we substitute the phenotypic variance-covariance matrix (P) for G to determine if the pattern of multivariate nonlinear selection in a natural population of Anolis cristatellus, an arboreal lizard from Puerto Rico, has influenced the evolution of genetic variances and covariances in this species. Although results varied among our estimates of P and fitness, and among our analytic techniques, we find significant evidence for congruence between nonlinear selection and P, suggesting that natural selection may have influenced the evolution of genetic constraint in this species.
性状间遗传方差和协方差的模式，总结在加性遗传方差-协方差矩阵 G 中，决定了种群将如何对线性自然选择做出反应。然而，G 本身也会因选择而进化。具体来说，我们预计，随着时间的推移，G 将与多元非线性自然选择的模式进化相适应。在这项研究中，我们用表型方差-协方差矩阵（P）代替 G，以确定波多黎各树栖蜥蜴 A. cristatellus 自然种群中多元非线性选择的模式是否影响了该物种遗传方差和协方差的进化。尽管我们对 P 和适应度的估计以及分析技术的结果各不相同，但我们发现非线性选择和 P 之间存在显著的一致性证据，这表明自然选择可能影响了该物种遗传约束的进化。
