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在高危经皮冠状动脉介入治疗中使用 Impella 2.5 导管系统为严重主动脉瓣狭窄患者提供血液动力学支持。

Hemodynamic support using the Impella 2.5 catheter system during high-risk percutaneous coronary intervention in a patient with severe aortic stenosis.

机构信息

Guthrie Health System, Sayre, Pennsylvania 18840, USA.

出版信息

J Interv Cardiol. 2010 Feb;23(1):66-9. doi: 10.1111/j.1540-8183.2009.00518.x. Epub 2009 Dec 17.

DOI:10.1111/j.1540-8183.2009.00518.x
PMID:20040004
Abstract

The Impella 2.5 catheter is a percutaneously implanted left ventricular assist device cleared by the Food and Drug Administration to provide circulatory support for up to 6 hours. The presence of aortic stenosis is deemed to be a contraindication to its use, and ongoing clinical trials exclude patients with an aortic valve area of 1.5 cm(2) or less. We describe a case of severe aortic stenosis with an estimated valve area of 0.9 cm(2) and severe ischemic cardiomyopathy in whom the Impella catheter was successfully used for high-risk multivessel percutaneous coronary intervention.

摘要

Impella 2.5 导管是一种经皮植入式左心室辅助设备,已获得美国食品和药物管理局批准,可提供长达 6 小时的循环支持。存在主动脉瓣狭窄被认为是其使用的禁忌症,正在进行的临床试验排除了主动脉瓣瓣口面积为 1.5 cm(2)或更小的患者。我们描述了一例严重的主动脉瓣狭窄伴估计瓣口面积为 0.9 cm(2)和严重缺血性心肌病的患者,该患者成功地使用了 Impella 导管进行高危多血管经皮冠状动脉介入治疗。

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Hemodynamic support using the Impella 2.5 catheter system during high-risk percutaneous coronary intervention in a patient with severe aortic stenosis.在高危经皮冠状动脉介入治疗中使用 Impella 2.5 导管系统为严重主动脉瓣狭窄患者提供血液动力学支持。
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A prospective feasibility trial investigating the use of the Impella 2.5 system in patients undergoing high-risk percutaneous coronary intervention (The PROTECT I Trial): initial U.S. experience.一项前瞻性可行性研究,调查在接受高危经皮冠状动脉介入治疗(PROTECT I 试验)的患者中使用 Impella 2.5 系统的情况:美国初步经验。
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The Role of Impella for Hemodynamic Support in Patients With Aortic Stenosis.Impella在主动脉瓣狭窄患者血流动力学支持中的作用
Curr Treat Options Cardiovasc Med. 2018 Apr 23;20(6):44. doi: 10.1007/s11936-018-0644-9.