Vakilzadeh F, Kolde G
Department of Dermatology, General Hospital of Hildesheim, Germany.
Br J Dermatol. 1991 Feb;124(2):191-4. doi: 10.1111/j.1365-2133.1991.tb00432.x.
An unusual ichthyosiform dermatosis with circumscribed areas of blistering hyperkeratoses as well as scaly areas was observed in five consecutive generations of a German family. Light and electron microscopical studies revealed oedema of the keratinocytes in the upper epidermis but no defects of tonofilaments and keratohyalin granules. We suggest that this type of ichthyosis exfoliativa inherited as an autosomal dominant trait represents a new and distinct entity.
在一个德国家庭的连续五代人中观察到一种不寻常的鱼鳞病样皮肤病，有局限性水疱性角化过度区域以及鳞屑区域。光镜和电镜研究显示上表皮角质形成细胞水肿，但张力细丝和透明角质颗粒无缺陷。我们认为这种作为常染色体显性性状遗传的剥脱性鱼鳞病代表一种新的独特类型。
