Wardinsky T D, Pagon R A, Kropp R J, Hayden P W, Clarren S K
Division of Medical Genetics, Children's Hospital and Medical Center, Seattle, WA 98105.
Cleft Palate Craniofac J. 1991 Jan;28(1):87-95. doi: 10.1597/1545-1569_1991_028_0087_ndscaw_2.3.co_2.
Nasal dermoid and sinus cysts (NDSC) are uncommon congenital anomalies that may have intracranial extension and can be associated with other anomalies. We identified 22 patients in a retrospective review of cases diagnosed with NDSC at our institution over the past 10 years. Nine (41 percent) had associated anomalies and ten (45 percent) had intracranial extension of the sinus. In half of the patients with intracranial extension, the sinus transversed either the cribriform plate or foramen cecum and attached to the dura; in the other half, the sinus extended to cysts within the falx or other brain structures. Of the patients with multiple anomalies, six (67 percent) had intracranial extension. Presurgical complications occurred in a total of eight patients (36 percent): two had meningitis, two had osteomyelitis, four had periorbital-nasal cellulitis, three had nasal abscess, and four had nose anomalies requiring rhinoplasty.
鼻皮样囊肿和鼻窦囊肿（NDSC）是罕见的先天性异常，可能会向颅内扩展，并可能与其他异常相关。在对我院过去10年诊断为NDSC的病例进行回顾性研究时，我们确定了22例患者。其中9例（41%）伴有其他异常，10例（45%）鼻窦有颅内扩展。在鼻窦有颅内扩展的患者中，一半的鼻窦穿过筛板或盲孔并附着于硬脑膜；另一半则延伸至大脑镰内或其他脑结构内的囊肿。在伴有多种异常的患者中，6例（67%）有颅内扩展。共有8例患者（36%）出现术前并发症：2例患有脑膜炎，2例患有骨髓炎，4例患有眶周-鼻蜂窝织炎，3例患有鼻脓肿，4例有需要鼻整形术的鼻畸形。
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