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急性髓系白血病M5一例的紧急治疗性白细胞单采术

Emergency therapeutic leukapheresis in a case of acute myeloid leukemia M5.

作者信息

Ranganathan Sudha, Sesikeran Shyamala, Gupta Vineet

机构信息

Apollo Hospital, Hyderabad.

出版信息

Asian J Transfus Sci. 2008 Jan;2(1):18-9. doi: 10.4103/0973-6247.39506.

Abstract

Cell separators in India are routinely used for plateletpheresis, peripheral blood stem cell collections and therapeutic plasma exchange. Therapeutic leukapheresis, particularly as an emergency procedure, has been uncommonly performed and reported. Here, a case of a 53-year-old male, diagnosed with acute myeloid leukemia subtype M5 (AML M5) with hyperleukocytosis, who underwent emergency leukaphereis, is reported. After two procedures, there was a decrease of WBC count by 85%, which enabled cytotoxic therapy to be initiated.

摘要

印度的细胞分离器通常用于血小板单采、外周血干细胞采集和治疗性血浆置换。治疗性白细胞单采,尤其是作为一种紧急程序,很少进行和报道。在此,报告一例53岁男性,诊断为急性髓系白血病M5亚型(AML M5)伴白细胞增多症,接受了紧急白细胞单采。经过两次操作后,白细胞计数下降了85%,从而能够开始进行细胞毒性治疗。

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