Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
J Gynecol Oncol. 2009 Dec;20(4):203-9. doi: 10.3802/jgo.2009.20.4.203. Epub 2009 Dec 28.
In this review, we summarized nine major clinical advances in gynecology which occurred in 2009. For cervical cancer, the role of human papillomavirus (HPV) test as a screening test, the efficacy of HPV vaccine for middle-aged women, randomized controlled trial (RCT) regarding concurrent chemoradiation using gemcitabine plus cisplatin, and the efficacy of pazopanib for metastatic or recurrent disease were chosen. For endometrial cancer, the necessity of systematic pelvic lymphadenectomy in early endometrial cancer was reviewed. For ovarian cancer, the timing of treatment initiation for recurrent ovarian cancer, dose-dense chemotherapy as postoperative adjuvant treatment, the best chemotherapy regimen for platinum-sensitive recurrent ovarian cancer, and the efficacy of target agents were selected. In addition, the results of RCT testing the benefit of ginger in preventing post-chemotherapy nausea were examined.
在这篇综述中，我们总结了 2009 年妇科领域的 9 项主要临床进展。对于宫颈癌，我们选择了人乳头瘤病毒（HPV）检测作为筛查试验、HPV 疫苗对中年女性的疗效、吉西他滨联合顺铂同期放化疗的随机对照试验（RCT），以及帕唑帕尼治疗转移性或复发性疾病的疗效。对于子宫内膜癌，我们回顾了早期子宫内膜癌系统盆腔淋巴结清扫的必要性。对于卵巢癌，我们选择了复发性卵巢癌治疗起始时间、密集化疗作为术后辅助治疗、铂类敏感复发性卵巢癌的最佳化疗方案，以及靶向药物的疗效。此外，我们还对 RCT 测试生姜预防化疗后恶心的疗效进行了研究。
