Ma Yan, Ou Yongkang, Chen Ling, Zheng Yiqing
Department of Otolaryngology, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510060, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Aug;23(16):728-30.
To evaluate the vestibular function of motion sickness.
VNG, which tests the vestibular function of horizontal semicircular canal, and CPT, which tests vestibulospinal reflex and judge proprioceptive, visual and vestibular status, were performed in 30 motion sickness patients and 20 healthy volunteers (control group). Graybiel score was recorded at the same time.
Two groups' Graybiel score (12.67 +/- 11.78 vs 2.10 +/- 6.23; rank test P<0.05), caloric test labyrinth value [(19.02 +/- 8.59) degrees/s vs (13.58 +/- 5.25) degrees/s; t test P<0.05], caloric test labyrinth value of three patients in motion sickness group exceeded 75 degrees/s. In computerized posturography testing (CPT), motion sickness patients were central type (66.7%) and disperse type (23.3%); all of control group were central type. There was statistical significance in two groups' CTP area, and motion sickness group was obviously higher than control group. While stimulating vestibulum in CPT, there was abnormality (35%-50%) in motion sickness group and none in control group. Generally evaluating CPT, there was only 2 proprioceptive hypofunction, 3 visual hypofunction, and no vestibular hypofunction, but none hypofunction in control group.
Motion sickness patients have high vestibular susceptible, some with vestibular hyperfunction. In posturography, a large number of motion sickness patients are central type but no vestibular hypofunction, but it is hard to keep balance when stimulating vestibulum.
评估晕动病的前庭功能。
对30例晕动病患者和20名健康志愿者（对照组）进行了检测水平半规管前庭功能的视频眼震图（VNG）以及检测前庭脊髓反射并判断本体感觉、视觉和前庭状态的冷热试验（CPT）。同时记录格雷比尔评分。
两组的格雷比尔评分（12.67±11.78 vs 2.10±6.23；秩和检验P<0.05），冷热试验迷路值[（19.02±8.59）°/s vs（13.58±5.25）°/s；t检验P<0.05]，晕动病组有3例患者的冷热试验迷路值超过75°/s。在姿势描记法测试（CPT）中，晕动病患者为中枢型（66.7%）和分散型（23.3%）；对照组均为中枢型。两组的CTP面积有统计学意义，晕动病组明显高于对照组。在CPT刺激前庭时，晕动病组有异常（35%-50%），而对照组无异常。综合评估CPT，仅有2例本体感觉功能减退、3例视觉功能减退，无前庭功能减退，但对照组无功能减退。
晕动病患者前庭易感性高，部分患者存在前庭功能亢进。在姿势描记法中，大量晕动病患者为中枢型但无前庭功能减退，但在刺激前庭时难以保持平衡。
