Chair of Microbiology, Jagiellonian University Medical College, Krakow, Poland.
Clin Microbiol Infect. 2010 Sep;16(9):1442-7. doi: 10.1111/j.1469-0691.2009.03139.x.
The present study reports the epidemiological investigations undertaken in one of Krakow's city hospitals regarding the source of infection and the routes of transmission of a group A streptococcus (Streptococcus pyogenes), using fluorescent in situ hybridization as a rapid method for detecting S. pyogenes carriage in the medical personnel involved. Four patients from the gynaecology department and two patients from the surgery department presented with clinical signs of infection. Characteristics of the S. pyogenes strains isolated from patients and from one medical staff member, including the emm gene and superantigens encoding genes, are described. All patients (four confirmed and two probable cases) survived; the operating theatre aid was identified as an S. pyogenes carrier and the source of the infections.
本研究报告了在克拉科夫市的一家医院进行的一项流行病学调查，该调查涉及 A 组链球菌（化脓性链球菌）的感染源和传播途径，使用荧光原位杂交作为一种快速方法来检测参与的医务人员中化脓性链球菌的携带情况。妇产科的四名患者和外科的两名患者出现了感染的临床症状。从患者和一名医务人员中分离出的化脓性链球菌菌株的特征，包括 emm 基因和超抗原编码基因，均已描述。所有患者（四名确诊病例和两名疑似病例）均存活；手术室助手被确定为化脓性链球菌携带者和感染源。
