Forrester Mathias B
Texas Department of State Health Services, Austin, TX 78756, USA.
Pediatr Emerg Care. 2010 Jan;26(1):15-8. doi: 10.1097/PEC.0b013e3181c330dc.
The purpose of this study was to describe the pattern of metaxalone ingestions by young children reported to poison control centers.
Cases were all metaxalone ingestions by patients aged 0 to 5 years reported to Texas poison control centers during 2000 to 2007. Cases with multiple substance ingestions and lack of follow-up were excluded. Cases were analyzed for selected demographic and clinical factors.
Of 148 total cases, 56.8% were boys. The distributions by management site were 56.1% on-site, 22.3% already at/en route to a health care facility, and 21.6% referred to a health care facility. Final medical outcomes were no effect for 90.5% cases, minor effect for 8.1%, moderate effect for 0.7%, and major effect for 0.7%. Specific clinical effects reported were drowsiness (11), vomiting (3), agitation (2), rash (1%), tachycardia (1), and ataxia (1).
Pediatric metaxalone ingestions reported to Texas poison control centers usually resulted in minor or no effect. Most ingestions did not require hospitalization.
本研究旨在描述向中毒控制中心报告的幼儿美他沙酮摄入情况。
病例为2000年至2007年期间向德克萨斯州中毒控制中心报告的0至5岁患者的所有美他沙酮摄入病例。排除多物质摄入和缺乏随访的病例。对选定的人口统计学和临床因素进行病例分析。
在148例病例中,56.8%为男孩。按处理地点分布为,56.1%在现场处理,22.3%已在/前往医疗机构,21.6%转诊至医疗机构。最终医疗结果为90.5%的病例无影响,8.1%有轻微影响,0.7%有中度影响,0.7%有重大影响。报告的具体临床症状有嗜睡(11例)、呕吐(3例)、烦躁(2例)、皮疹(1%)、心动过速(1例)和共济失调(1例)。
向德克萨斯州中毒控制中心报告的儿童美他沙酮摄入通常导致轻微影响或无影响。大多数摄入情况无需住院治疗。