Sampayo Esther Maria, Chew Amber, Zorc Joseph J
Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA.
Pediatr Emerg Care. 2010 Jan;26(1):1-5. doi: 10.1097/PEC.0b013e3181c32e9d.
To develop and validate a brief assessment instrument for persistent asthma symptoms in a pediatric emergency department (ED) population.
Parents of children aged 1 to 18 years being discharged home after treatment for acute asthma in an urban children's hospital completed a 6-item screen for persistent symptoms that had been developed from national guidelines and previously validated. During a follow-up phone call 4 weeks after the ED visit, the instrument was repeated. An 8-item asthma-related quality-of-life (ARQOL) instrument was also administered at both times to assess construct validity. Item analysis assessed the performance of individual items and their combination versus the full instrument.
Four hundred thirty-three children were enrolled, and 361 patients (83%) had complete data. Sensitivity and predictive value were calculated for the full screen and combination of items in detecting persistent symptoms at baseline and follow-up. A 3-item version included symptoms with activity, symptoms at night, and need for rescue albuterol. This version was 96% sensitive (95% confidence interval, 92-99) for persistent symptoms compared with the 6-item screen, and 69% (95% confidence interval, 62-76) of the participants continued to report persistent symptoms 4 weeks after the visit. For both screens, subjects with persistent symptoms had significantly worse ARQOL score at baseline and follow-up.
A brief screen can identify persistent symptoms in pediatric ED patients with good sensitivity compared with a longer instrument. Most of these patients will continue to report persistent symptoms and reduced ARQOL score 1 month after the ED visit and may be candidates for additional interventions in the ED to improve long-term asthma care.
开发并验证一种用于儿科急诊科人群持续性哮喘症状的简短评估工具。
在一家城市儿童医院接受急性哮喘治疗后出院的1至18岁儿童的家长,完成了一项基于国家指南制定并经先前验证的6项持续性症状筛查。在急诊科就诊4周后的随访电话中,重复使用该工具。还在两个时间点均使用了一种8项哮喘相关生活质量(ARQOL)工具来评估结构效度。项目分析评估了各个项目及其组合与完整工具相比的表现。
共纳入433名儿童,361名患者(83%)有完整数据。计算了完整筛查和项目组合在基线和随访时检测持续性症状的敏感性和预测值。一个3项版本包括活动时的症状、夜间症状以及使用沙丁胺醇急救的需求。与6项筛查相比,该版本对持续性症状的敏感性为96%(95%置信区间,92 - 99),69%(95%置信区间,62 - 76)的参与者在就诊4周后仍报告有持续性症状。对于这两种筛查,有持续性症状的受试者在基线和随访时的ARQOL评分均显著更差。
与更长的工具相比,一种简短筛查能够以良好的敏感性识别儿科急诊科患者的持续性症状。这些患者中的大多数在急诊科就诊1个月后仍会继续报告持续性症状且ARQOL评分降低,可能是急诊科额外干预以改善长期哮喘护理的候选对象。