Kunkov Sergey, Crain Ellen F
Division of Pediatric Emergency Medicine, Department of Pediatrics, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
J Asthma. 2010 Jun;47(5):545-50. doi: 10.3109/02770901003795323.
To explore the utility of two measures, Risk for Nonadherence (RN) and Admitted Nonadherence (AN), developed in a national sample of children with chronic asthma, for predicting short-term morbidity among children following a pediatric emergency department (PED) visit for acute asthma and to compare verbal and self-completion of these measures.
DESIGN, SETTING, AND PARTICIPANTS: Prospective cohort study of children 3 to 11 years of age presenting to a PED with an acute asthma exacerbation. Caretakers were randomized to self-completion of a questionnaire assessing RN and AN or to verbally respond to the same questionnaire administered by a research assistant. Five asthma morbidity indicators were collected at 2, 4, and 8 weeks following discharge from the PED.
One hundred fifty-four patients were enrolled. There were no significant differences in asthma severity, RN, or AN, or the number of items missing on questionnaires between the self-completion and verbal administration groups. Patients with a RN score >4 had an adjusted odds of 3.67 (95% confidence interval [CI] 1.57-8.58) for waking >2 nights due to asthma symptoms. The adjusted odds of patients with any AN to report needing >4 days of rescue asthma medication was 3.16 (95% CI 1.37-7.26).
RN and AN were both associated with morbidity indices following an acute asthma exacerbation and can identify children at risk for increased short-term morbidity regardless of the method of questionnaire administration. Assessment of RN and AN by self-administered questionnaire during an ED visit for asthma maybe feasible.
探讨在全国慢性哮喘儿童样本中开发的两种测量方法,即不依从风险(RN)和已确认不依从(AN),对预测儿科急诊科(PED)急性哮喘就诊儿童的短期发病率的效用,并比较这些测量方法的口头填写和自行填写情况。
设计、设置和参与者:对3至11岁因急性哮喘加重就诊于PED的儿童进行前瞻性队列研究。照顾者被随机分为自行填写评估RN和AN的问卷,或口头回答由研究助理发放的相同问卷。在PED出院后2周、4周和8周收集五项哮喘发病率指标。
共纳入154例患者。自行填写组和口头填写组在哮喘严重程度、RN或AN以及问卷上缺失的项目数量方面没有显著差异。RN评分>4的患者因哮喘症状醒来超过2晚的调整后比值比为3.67(95%置信区间[CI]1.57 - 8.58)。有任何AN的患者报告需要超过4天的哮喘急救药物的调整后比值比为3.16(95%CI 1.37 - 7.26)。
RN和AN均与急性哮喘加重后的发病率指标相关,并且无论问卷发放方式如何,都可以识别出短期发病率增加风险的儿童。在哮喘急诊就诊期间通过自行填写问卷评估RN和AN可能是可行的。