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儿童和青少年骨肉瘤的发病率及生存率

Incidence and survival rates of children and young adults with osteogenic sarcoma.

作者信息

Homa D M, Sowers M R, Schwartz A G

机构信息

Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor 48109.

出版信息

Cancer. 1991 Apr 15;67(8):2219-23. doi: 10.1002/1097-0142(19910415)67:8<2219::aid-cncr2820670837>3.0.co;2-b.

DOI:10.1002/1097-0142(19910415)67:8<2219::aid-cncr2820670837>3.0.co;2-b
PMID:2004344
Abstract

Gender-specific and race-specific incidence and survival rates of osteogenic sarcoma over a 14-year period are presented for persons aged 0 to 24 years from eight Surveillance, Epidemiology, and End Results (SEER) registries. They were no significant gender or racial differences in age at diagnosis. There was no significant gender difference in overall incidence. Although incidence rates were slightly higher in blacks compared with whites, the difference was not significant after controlling for multiple comparisons. Females (median, 74 months) survived longer than males (median, 29 months), although this difference weakened after controlling for stage. No racial differences in survival were observed. White females survived the longest (median, 94 months), followed by black females (median, 41 months), black males (median, 34 months), and white males (median, 29 months). This striking difference in survival should be explored more fully.

摘要

来自八个监测、流行病学和最终结果(SEER)登记处的数据呈现了0至24岁人群在14年期间骨肉瘤的性别和种族特异性发病率及生存率。诊断时的年龄在性别和种族上无显著差异。总体发病率在性别上无显著差异。尽管黑人的发病率略高于白人,但在进行多重比较校正后,差异并不显著。女性(中位数为74个月)的生存期长于男性(中位数为29个月),不过在对分期进行校正后,这种差异有所减弱。未观察到生存方面的种族差异。白人女性生存期最长(中位数为94个月),其次是黑人女性(中位数为41个月)、黑人男性(中位数为34个月)和白人男性(中位数为29个月)。这种显著的生存差异应得到更充分的探究。

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