Suntornlimsiri Watcharin, Naunkeaw Kanchana
Department of Obstetrics and Gynecology, Nakornping Hospital, Chiang Mai 50180, Thailand.
J Med Assoc Thai. 2009 Dec;92(12):1567-72.
To determine the correlation of clinical factors and maternal perceptions of pain with genetic amniocentesis.
This prospective study of midtrimester, singleton pregnancies was conducted between February 2007 and March 2008. Study variables included patient dermographics, previous amniocentesis, previous abdominal surgery, maternal anxiety score, abdominal wall thickness, needle insertion through placenta and the depth of needle insertion. Maternal pain with performing amniocentesis was subjectively quantified with the Thai short-form McGill Pain Questionnaire. The independent T-test, one way ANOVA and linear regression were used for analysis, a probability value of < 0.05 was considered significant.
One hundred and twenty-five pregnant women participated in the present study: 18.4% reported no pain, 69.6% described the pain as mild, 11.2% described the pain as discomforting and 0.8% described the pain as horrible. Mean intensity of pain was 2.1 +/- 1.9 (on a scale 0-10). Pain was most often described as fearful, shooting, throbbing and sharp. Parity, gestational age, maternal BMI, anxiety score, previous surgery, needle insertion through the placenta, abdominal wall thickness and the depth of needle insertion were not correlated with perceived pain.
Most of the women reported no pain or mild or discomfort with genetic amniocentesis. Clinical factors were not associated with maternal perceptions of pain.
确定临床因素及孕妇对疼痛的感受与基因羊膜穿刺术之间的相关性。
本前瞻性研究于2007年2月至2008年3月对孕中期单胎妊娠进行。研究变量包括患者人口统计学特征、既往羊膜穿刺术史、既往腹部手术史、孕妇焦虑评分、腹壁厚度、穿刺针穿过胎盘情况及穿刺针插入深度。采用泰国版简化麦吉尔疼痛问卷对孕妇进行羊膜穿刺术时的疼痛进行主观量化。采用独立样本t检验、单因素方差分析和线性回归进行分析，P值<0.05被认为具有统计学意义。
125名孕妇参与了本研究：18.4%报告无疼痛，69.6%称疼痛轻微，11.2%称疼痛不适，0.8%称疼痛难忍。疼痛平均强度为2.1±1.9（0-10分）。疼痛最常被描述为恐惧、刺痛、搏动性和尖锐性。产次、孕周、孕妇体重指数、焦虑评分、既往手术史、穿刺针穿过胎盘情况、腹壁厚度及穿刺针插入深度与疼痛感受均无相关性。
大多数女性报告基因羊膜穿刺术无疼痛或疼痛轻微或不适。临床因素与孕妇的疼痛感受无关。
