Chawla Bobby, Iqbal Fahad M, Chawla Manjeet S
Department of Medicine, West Virginia University, Morgantown, WV 26506-9162, USA.
Compr Ther. 2009 Fall-Winter;35(3-4):199-203.
Erythropoietin refractory anemias represent a continuing and increasing burden on the healthcare system. The current practice of providing these patients with rHuEPO does not seem to be working. Fewer than 50% of patients respond in some studies. We demonstrate that androgens have multiple benefits in this population. They control anemia and stop transfusion dependence and improve nutritional parameters. In some patients, they also have a salutary effect on both white blood cell and platelet counts.
促红细胞生成素难治性贫血给医疗系统带来的负担持续加重。目前给这些患者使用重组人促红细胞生成素（rHuEPO）的做法似乎并不奏效。在一些研究中，不到50%的患者有反应。我们证明雄激素对这一人群有多种益处。它们能控制贫血，终止输血依赖并改善营养参数。在一些患者中，它们对白细胞和血小板计数也有有益影响。
