Gray Sara G, Hunter Stuart A, Stone Maria R, Gookin Jody L
Department of Clinical Sciences, North Carolina State University, Raleigh, NC 27606, USA.
Am J Vet Res. 2010 Jan;71(1):76-81. doi: 10.2460/ajvr.71.1.76.
To determine whether Tritrichomonas foetus infection resides in reproductive tract tissues from cats housed for breeding and for which a high prevalence of colonic T foetus infection has been reported.
61 purebred cats in 36 catteries undergoing elective ovariohysterectomy or castration and for which reproductive tract tissues, feces, and a reproductive history were obtained.
Reproductive tract tissues were examined for T foetus via light microscopy, immunohistochemical analysis, and PCR assay. History of reproductive tract disease was examined to detect statistical associations with identified or reported exposure to colonic T foetus infection.
15 of 61 (25%) cats and 22 of 33 (67%) catteries were identified with active or reported T foetus infection. Light microscopic, immunohistochemical, or molecular evidence of T foetus infection of the reproductive tract was not detected in any cats, including 15 cats with colonic T foetus infection, 29 cats residing in a cattery in which T foetus-infected cats were identified, and 8 cats for which gross or light microscopic evidence of reproductive tract disease was identified. There were no differences in total number of litters, number of litters per breeding, kitten mortality rate, or birth defects between cats or catteries infected with T foetus and those for which T foetus infection was not identified.
No evidence of reproductive tract colonization by T foetus was detected in this study. Accordingly, it is unlikely that reproductive tract infection with T foetus plays an important role in overall disease transmission.
确定胎儿三毛滴虫感染是否存在于用于繁殖且报告结肠胎儿三毛滴虫感染患病率较高的猫的生殖道组织中。
36个猫舍中的61只纯种猫，这些猫接受择期卵巢子宫切除术或去势手术，并获取了生殖道组织、粪便和繁殖史。
通过光学显微镜、免疫组织化学分析和聚合酶链反应检测生殖道组织中的胎儿三毛滴虫。检查生殖道疾病史，以检测与已确定或报告的结肠胎儿三毛滴虫感染暴露之间的统计学关联。
61只猫中有15只（25%）和33个猫舍中有22个（67%）被确定患有活动性或报告的胎儿三毛滴虫感染。在任何猫中均未检测到生殖道胎儿三毛滴虫感染的光学显微镜、免疫组织化学或分子证据，包括15只结肠胎儿三毛滴虫感染的猫、29只居住在已鉴定出胎儿三毛滴虫感染猫的猫舍中的猫，以及8只具有生殖道疾病肉眼或光学显微镜证据的猫。感染胎儿三毛滴虫的猫和未鉴定出胎儿三毛滴虫感染的猫或猫舍之间，在总产仔数、每次繁殖产仔数、小猫死亡率或出生缺陷方面没有差异。
本研究未检测到胎儿三毛滴虫在生殖道定植的证据。因此，胎儿三毛滴虫生殖道感染在总体疾病传播中不太可能起重要作用。
