头孢噻吩和头孢唑林在缓冲液或人血清中的稳定性比较。
Comparative stability of cephalothin and cefazolin in buffer or human serum.
作者信息
Pitkin D, Actor P, Filan J J, White R, Weisbach J A
出版信息
Antimicrob Agents Chemother. 1977 Aug;12(2):284-5. doi: 10.1128/AAC.12.2.284.
Abstract
A marked loss in potency was observed when cephalothin was incubated for 5 h in human serum at 37 degrees C. Cefazolin was stable under these conditions.
摘要
当头孢噻吩在37摄氏度的人血清中孵育5小时后，观察到其效价显著降低。头孢唑林在这些条件下是稳定的。
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本文引用的文献
1
Stability of cephalosporins in horse serum.头孢菌素在马血清中的稳定性。
Antimicrob Agents Chemother. 1977 Jan;11(1):174-5. doi: 10.1128/AAC.11.1.174.
2
Comparative stability of cephalosporins in aqueous solution: kinetics and mechanisms of degradation.头孢菌素在水溶液中的相对稳定性：降解动力学与机制
J Pharm Sci. 1976 Nov;65(11):1563-74. doi: 10.1002/jps.2600651104.
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