Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.
J Am Acad Orthop Surg. 2010 Jan;18(1):10-9. doi: 10.5435/00124635-201001000-00003.
Open fractures of the tibial diaphysis are often associated with severe bone and soft-tissue injury. Contamination of the fracture site and devitalization of the soft-tissue envelope greatly increase the risk of infection, nonunion, and wound complications. Management of open tibial shaft fractures begins with a thorough patient evaluation, including assessment of the bone and soft tissue surrounding the tibial injury. Classification of these injuries according to the system of Gustilo and Anderson at the time of surgical débridement is useful in guiding treatment and predicting outcomes. Administration of antibiotic prophylaxis as soon as possible after injury as well as urgent and thorough débridement, irrigation, and bony stabilization are done to minimize the risk of infection and improve outcomes. The use of antibiotic bead pouches and negative-pressure wound therapy has proved to be efficacious for the acute, temporary management of severe bone and soft-tissue defects.
胫骨骨干开放性骨折常伴有严重的骨和软组织损伤。骨折部位的污染和软组织套的失活大大增加了感染、骨不连和伤口并发症的风险。开放性胫骨骨干骨折的治疗始于对患者的全面评估,包括对胫骨损伤周围的骨骼和软组织的评估。在手术清创时根据 Gustilo 和 Anderson 系统对这些损伤进行分类有助于指导治疗和预测结果。尽快给予抗生素预防,以及紧急和彻底的清创、冲洗和骨固定,以尽量降低感染风险并改善结果。抗生素珠袋和负压伤口治疗已被证明可有效治疗严重的骨和软组织缺损的急性和临时管理。