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[开放性骨折的初期软组织处理]

[Primary soft tissue management in open fracture].

作者信息

Riechelmann F, Kaiser P, Arora R

机构信息

Universitätsklinik für Unfallchirurgie, Medizinische Universität Innsbruck, Anichstraße 35, 6020, Innsbruck, Österreich.

出版信息

Oper Orthop Traumatol. 2018 Oct;30(5):294-308. doi: 10.1007/s00064-018-0562-8. Epub 2018 Sep 4.

Abstract

OBJECTIVE

Debridement of soft tissue and bone in an open fracture situation to minimize infection risk and achieve primary skin closure, or to provide conditions for early soft tissue coverage.

INDICATIONS

Indications are Gustilo-Anderson grade I-III A-C open fractures.

CONTRAINDICATIONS

Contraindications are injuries requiring amputation, burns, and life-threatening injuries which make appropriate treatment temporarily impossible.

SURGICAL TECHNIQUE

Removal of gross contamination and macroscopic contaminants; debridement of the wound; complete resection of contaminated and dirty tissue; sparse step-by-step resection of contaminated or non-vital wound and bone margins until vital, bleeding tissue begins; low-pressure irrigation with isotonic irrigation fluid; diagnostic biopsies for microbiological testing; reduction of dead space by interpositioning of muscle or cement spacers loaded with local antibiotics; primary wound closure if tension-free closure possible; otherwise, if resources and knowhow permit and satisfactory clean debridement was achieved, local flap; if flap impossible, debridement not satisfactory, secondary tissue necrosis likely, potential remaining contamination or contamination with fecal matter, then vacuum-assisted closure therapy.

POSTOPERATIVE MANAGEMENT

Wound inspection on the second postoperative day, generous indication for second-look surgery after 36-48 h, wound inspection on the second postoperative day, wound inspection every other day, primary antibiotic prophylaxis with a first- or second-generation cephalosporin (e. g., cefuroxime), and adaptation of antibiotic therapy according to susceptibility screening.

RESULTS

Infection rates of 2-4.7% are reported for immediate primary wound closure in Gustilo-Anderson grade I, II, and III A open fractures. For Gustilo-Anderson grade III B, good wound healing, bony consolidation, and no need for secondary surgery was reported in 86.7% when primary wound closure was achieved.

摘要

目的

在开放性骨折情况下对软组织和骨骼进行清创,以将感染风险降至最低并实现一期皮肤缝合,或为早期软组织覆盖创造条件。

适应症

适用于Gustilo-Anderson I-III A-C级开放性骨折。

禁忌症

禁忌证包括需要截肢的损伤、烧伤以及危及生命的损伤,这些损伤使适当治疗暂时无法进行。

手术技术

清除严重污染和肉眼可见的污染物;清创伤口;彻底切除受污染和不洁组织;逐步稀疏切除受污染或无活力的伤口及骨边缘,直至出现有活力的出血组织;用等渗冲洗液进行低压冲洗;进行诊断性活检以进行微生物检测;通过置入装有局部抗生素的肌肉或骨水泥间隔物来减少死腔;若能无张力缝合则进行一期伤口缝合;否则,若资源和技术允许且清创满意,则行局部皮瓣转移;若无法进行皮瓣转移、清创不满意、可能出现继发性组织坏死、存在潜在残留污染或粪便污染,则采用负压封闭引流治疗。

术后管理

术后第二天检查伤口,36-48小时后酌情进行二次探查手术,术后第二天检查伤口,每隔一天检查伤口,用第一代或第二代头孢菌素(如头孢呋辛)进行预防性抗生素治疗,并根据药敏筛查调整抗生素治疗。

结果

据报道,Gustilo-Anderson I级、II级和III A级开放性骨折一期伤口立即缝合的感染率为2-4.7%。对于Gustilo-Anderson III B级骨折,若实现一期伤口缝合,86.7%的患者伤口愈合良好、骨愈合且无需二次手术。

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