Department of Neurological Sciences, Christian Medical College, Vellore 632004, India.
Int J Surg. 2010;8(2):100-4. doi: 10.1016/j.ijsu.2009.12.006. Epub 2010 Jan 4.
Neurocysticercosis (NCC) is caused by the larval form of the pork tapeworm Taenia solium and is the commonest parasitic infestation of the central nervous system. NCC is usually managed medically but in some instances surgery is required. Magnetic resonance imaging (MRI) and computed tomography (CT) are often able to provide the diagnosis of NCC in most patients with intraventricular and parenchymal cysts but in patients with hydrocephalus without any cysts, the diagnosis is confirmed by the presence of cysticercal antibodies in the serum. Surgery is usually recommended for intraventricular cysts, hydrocephalus, large cisternal cysts, large parenchymal cysts and when the diagnosis is not certain on imaging studies. For intraventricular cysts, endoscopic surgery is the procedure of choice as it is minimally invasive. For incompletely excised cysts and cysts or granulomas in locations such as the spinal cord, medical treatment with steroids and albendazole is recommended. Hydrocephalus is treated with a ventriculo-peritoneal shunt but shunts in these patients suffer from frequent obstructions and require multiple revisions. The outcome for patients with intraventricular and parenchymal cysts is usually good but for those with hydrocephalus associated with cisternal or racemose cysts and with cysticercotic meningitis, the mortality is high.
脑囊尾蚴病(NCC)由猪肉绦虫幼虫引起,是中枢神经系统最常见的寄生虫感染。NCC 通常采用药物治疗,但在某些情况下需要手术。磁共振成像(MRI)和计算机断层扫描(CT)通常能够为大多数脑室和实质囊肿患者提供 NCC 的诊断,但对于没有任何囊肿的脑积水患者,通过血清中囊尾蚴抗体的存在来确诊。手术通常推荐用于脑室囊肿、脑积水、大池囊肿、大实质囊肿和影像学检查不确定的情况。对于脑室囊肿,内镜手术是首选方法,因为它是微创的。对于未完全切除的囊肿和脊髓等部位的囊肿或肉芽肿,推荐使用类固醇和阿苯达唑进行药物治疗。脑积水采用脑室-腹腔分流术治疗,但这些患者的分流管经常发生阻塞,需要多次修改。脑室和实质囊肿患者的预后通常良好,但对于与池状或蔓状囊肿和囊尾蚴性脑膜炎相关的脑积水患者,死亡率很高。