Hamamoto Filho Pedro Tadao, Norcia Luiz Fernando, Fleury Agnès, Zanini Marco Antônio
Botucatu Medical School, UNESP-Universidade Estadual Paulista, Botucatu 18618-686, Brazil.
Instituto de Investigaciones Biomedicas, UNAM-Universidad Nacional Autónoma de Mexico, Ciudad de Mexico 14269, Mexico.
Pathogens. 2024 Feb 29;13(3):218. doi: 10.3390/pathogens13030218.
Neurocysticercosis (NCC) is a common parasitic disease of the central nervous system (CNS) in low- and middle-income countries. The infection is pleomorphic, caused by the larval form of the cestode, , and part of the heterogeneity of its clinical presentations is associated with the localization of the parasite within the CNS. Changes in the current epidemiological trends of NCC indicate that extra-parenchymal NCC is proportionally becoming more frequent. Extraparenchymal NCC is commonly accompanied by raised intracranial hypertension due to hydrocephalus, which is an emergency requiring cyst extirpation by surgical intervention to relieve the symptoms. Although less frequent, parenchymal cysts may also reach giant sizes requiring urgent surgical treatment. Finally, there is an advancement in the comprehension of the association between NCC and epilepsy-and patients with drug-resistant seizures are candidates for surgical treatment. In this narrative review, we summarize the present state of knowledge to update the current trends in the role of surgery in the treatment of NCC.
神经囊尾蚴病（NCC）是低收入和中等收入国家常见的中枢神经系统（CNS）寄生虫病。该感染具有多形性，由绦虫的幼虫形式引起，其临床表现的部分异质性与寄生虫在中枢神经系统内的定位有关。NCC当前流行病学趋势的变化表明，脑实质外NCC的比例正变得越来越高。脑实质外NCC通常因脑积水而伴有颅内压升高，这是一种紧急情况，需要通过手术干预摘除囊肿以缓解症状。虽然较少见，但脑实质囊肿也可能发展到巨大尺寸，需要紧急手术治疗。最后，在理解NCC与癫痫之间的关联方面有了进展，耐药性癫痫发作的患者是手术治疗的候选对象。在这篇叙述性综述中，我们总结了当前的知识状况，以更新手术在NCC治疗中作用的当前趋势。
