Nakamura Shin-ichi, Hayashidani Hideki, Iwata Taketoshi, Takada Mariko, Une Yumi
Laboratory of Veterinary Pathology, Azabu University, Sagamihara, Kanagawa 229-8501, Japan.
J Vet Med Sci. 2009 Dec;71(12):1657-9. doi: 10.1292/jvms.001657.
A captive male Bolivian squirrel monkey (Saimiri boliviensis) of less than 1 year of age died following diarrhea and debilitation on the day of death. At necropsy, necrotizing enteritis accompanied with enlarged Peyer's patches, solitary lymphatic follicles and mesenteric lymph nodes, and multiple yellowish-white nodules in the spleen and liver were found. Histopathologically, these lesions were necrotizing inflammation containing Gram-negative bacilli. Yersinia pseudotuberculosis serotype 7 was isolated from the spleen and liver. The virF gene, which is an essential virulent plasimid (pYV) in pathogenic Y. pseudotuberculosis isolates, and the ypmA gene, which is a superantigenic toxin, were detected in the isolates. This is the first report of a fatal case of Yersinia pseudotuberculosis 7 infection in the world.
一只不到1岁的圈养雄性玻利维亚松鼠猴在死亡当天出现腹泻和身体虚弱后死亡。尸检时，发现坏死性肠炎伴有派伊尔氏结、孤立淋巴滤泡和肠系膜淋巴结肿大，以及脾脏和肝脏中有多个黄白色结节。组织病理学检查显示，这些病变为含有革兰氏阴性杆菌的坏死性炎症。从脾脏和肝脏中分离出了7型假结核耶尔森菌。在分离株中检测到了致病假结核耶尔森菌分离株中必需的毒力质粒（pYV）上的virF基因和一种超抗原毒素ypmA基因。这是世界上首例7型假结核耶尔森菌感染致死病例的报告。
