通过与零价铁卡宾或乙烯基烯酮配合物反应将六氟丁炔引入呋喃或苯酚中。
Incorporation of hexafluorobutyne into furans or phenols via reaction with iron(0) carbene or vinylketene complexes.
作者信息
Akhani Ravish K, Schnatter Wayne F K
机构信息
Long Island University, Department of Chemistry and Biochemistry, Brooklyn, NY 11201.
出版信息
Tetrahedron Lett. 2009;50:930-932. doi: 10.1016/j.tetlet.2008.12.037.
Abstract
Reaction of iron(0) carbene complexes with hexafluorobut-2-yne produces 3,4-bis(trifluoromethylated)furans in a process that is favored for electron rich carbenes. No traces of furannulation or benzannulation are observed with Group 6 Fischer carbenes. Reaction of hexafluorobut-2-yne with a vinylketene iron(0) complex gives a 2,3-bis-trifluoromethylated phenol.
摘要
零价铁卡宾配合物与六氟-2-丁炔反应生成3,4-双（三氟甲基化）呋喃，该过程有利于富电子卡宾。对于第6族菲舍尔卡宾，未观察到呋喃化或苯并环化的痕迹。六氟-2-丁炔与乙烯基乙烯酮零价铁配合物反应生成2,3-双三氟甲基化苯酚。
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