Miki Koji, Nishino Fumiaki, Ohe Kouichi, Uemura Sakae
Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
J Am Chem Soc. 2002 May 15;124(19):5260-1. doi: 10.1021/ja025776+.
The reaction of conjugated ene-yne-ketones 3 with a variety of alkenes in the presence of a catalytic amount of Cr(CO)(5)(THF) at room temperature gives (2-furyl)cyclopropanes in good yields. These cyclopropanation reactions proceed via (2-furyl)carbene-chromium intermediates 4 formed in situ from ene-yne-ketones 3. Late transition metals, such as RuCl(2)(CO)(3), RhCl(cod), PdCl(2), and PtCl(2), also catalyze effectively the cyclopropanation of styrene with 3.
