Department of Psychiatry, College of Medicine, Inha University, Incheon, Korea.
Psychiatry Investig. 2009 Jun;6(2):112-4. doi: 10.4306/pi.2009.6.2.112. Epub 2009 Jun 30.
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by vertical supranuclear palsy and parkinsonian symptoms. The neuropsychiatric symptoms of PSP include anhedonia, depressed mood and cognitive impairment. Patients with PSP have an increased risk for developing depressive disorders within the next year. However, it is rare to find that major depressive disorder was the antecedent diagnosis of a patient who was later diagnosed with PSP. We present here a patient who suffered from PSP with repetitive falls, a masked face and dysarthria after developing a major depressive disorder.
进行性核上性麻痹（PSP）是一种以垂直性核上麻痹和帕金森症状为特征的神经退行性疾病。PSP 的神经精神症状包括快感缺失、情绪低落和认知障碍。PSP 患者在未来一年内发展为抑郁障碍的风险增加。然而，罕见的是发现，在被诊断为 PSP 的患者中，主要抑郁障碍是其先前的诊断。我们在此介绍一位患者，他在患发重度抑郁症后出现 PSP，表现为反复跌倒、面具脸和构音障碍。
