Department of Gastroenterology, Klinikum Memmingen, Memmingen, Germany.
Aliment Pharmacol Ther. 2010 Mar;31(6):634-9. doi: 10.1111/j.1365-2036.2009.04225.x. Epub 2009 Dec 25.
Endoscopic balloon dilation has been shown to be an alternative to surgery in the treatment of Crohn's symptomatic strictures.
To analyse the impact of the type of the strictures -de novo or anastomotic - their location and their length on the outcome of endoscopic balloon dilation.
Between December 1999 and June 2008, 55 patients underwent 93 balloon dilations for 74 symptomatic strictures. One stricture was located in the duodenum, 39 strictures were in the terminal ileum, 17 at the ileocoecal anastomosis after a preceding resection and 17 in the colon.
Endoscopic treatment was successful in 76% of the patients during an observation period of 44 (1-103) months. Of the patients, 24% required surgery. All patients who underwent surgery had de novo strictures in the terminal ileum. These strictures were significantly longer compared with the ileal strictures that responded to endoscopic treatment [7.5 (1-25) cm vs. 2.5 (1-25) cm; P = 0.006].
The long-term success of endoscopic balloon dilation depends on the type of the strictures, their location and their length. Failure of endoscopic treatment was observed only in long-segment strictures in the terminal ileum.
内镜球囊扩张已被证明是治疗克罗恩病症状性狭窄的手术替代方法。
分析狭窄的类型（新发或吻合口）、位置和长度对内镜球囊扩张治疗结果的影响。
1999 年 12 月至 2008 年 6 月，55 例患者因 74 例症状性狭窄接受了 93 次球囊扩张。1 例狭窄位于十二指肠，39 例狭窄位于末端回肠，17 例狭窄位于先前切除后的回盲肠吻合口，17 例狭窄位于结肠。
在 44（1-103）个月的观察期内，76%的患者内镜治疗成功。24%的患者需要手术。所有接受手术的患者均为末端回肠新发狭窄，与内镜治疗有效的回肠狭窄相比，这些狭窄明显更长[7.5（1-25）cm 比 2.5（1-25）cm；P=0.006]。
内镜球囊扩张的长期疗效取决于狭窄的类型、位置和长度。仅在末端回肠长段狭窄时观察到内镜治疗失败。
