一种新型FMS样酪氨酸激酶基因的分离与染色体定位
Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene.
作者信息
Rosnet O, Matteï M G, Marchetto S, Birnbaum D
机构信息
U.119 INSERM, Marseille, France.
出版信息
Genomics. 1991 Feb;9(2):380-5. doi: 10.1016/0888-7543(91)90270-o.
PMID:2004790
Abstract
We have isolated and sequenced part of a new gene of the tyrosine kinase family. This gene, called FLT3, has strong sequence similarities with members of a group of genes encoding growth factor receptors: FMS, KIT, and PDGFR. We have localized the human FLT3 gene to chromosome 13, band q12, and its mouse homolog to chromosome 5, region G.
摘要
我们已经分离并测序了酪氨酸激酶家族一个新基因的部分序列。这个名为FLT3的基因，与一组编码生长因子受体的基因成员：FMS、KIT和PDGFR，有很强的序列相似性。我们已经将人类FLT3基因定位到13号染色体q12带，其小鼠同源基因定位到5号染色体G区域。
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