Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Pediatrics. 2010 Jan;125 Suppl 1:S1-18. doi: 10.1542/peds.2009-1878C.
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.
自闭症谱系障碍(ASD)是一种常见且具有临床异质性的神经发育障碍。胃肠道疾病和相关症状在 ASD 患者中经常被报告,但这些疾病的患病率和最佳治疗等关键问题尚未被完全理解。在识别和描述 ASD 患者的胃肠道功能障碍时,一个核心难点是许多受影响个体存在沟通困难。一个多学科小组审查了医学文献,旨在为该患者群体的胃肠道问题的诊断评估和管理提供循证建议。专家组得出的结论是,目前还没有基于证据的推荐。专家组的共识专家意见是,ASD 患者在胃肠道问题的诊断和治疗中应得到与非 ASD 患者相同的全面性和标准的医疗护理。护理人员应该意识到,ASD 患者的行为问题可能是潜在医疗状况的主要或唯一症状,包括一些胃肠道疾病。对于这些患者,行为和医疗护理的整合可能最有益。确定了未来研究的优先事项,以推进我们对 ASD 患者胃肠道疾病的理解和管理。