Tarazona Santabalbina F J, Belenguer Varea A, Doménech Pascual J R, Gac Espínola H, Cuesta Peredo D, Medina Domínguez L, Salvador Pérez M I, Avellana Zaragoza J A
Servicio de Geriatría, Hospital de la Ribera, Alzira, Valencia, España.
Nutr Hosp. 2009 Nov-Dec;24(6):724-31.
comprehensive geriatric assessment includes examination of the nutritional status given the high prevalence of hyponutrition in this kind of patients, particularly in patients with associated cognitive impairment. Scales for screening the nutritional status include questions on self-perception difficult to answer by demented elder patients.
To study the specificity, the positive predictive value, and the sensitivity of the MNA scale to detect malnutrition in patients diagnosed with Alzheimer's disease with advanced cognitive impairment.
a population-based descriptive study with a sample of 52 patients older than 70 years, institutionalized, and with moderate-severe Alzheimer's disease was designed. The sensitivity, specificity, and positive predictive value of MNA scale were studied regarding the parameters on malnutrition of the American Institute of Nutrition (AIN).
the sensitivity, specificity, and positive predictive values were 60%, 94.7%, and 93.8%, respectively. There was a significant correlation (p < 0.001) between the score obtained with the MNA Scale and the Tinneti's Risk of Fall Scale (r = 0.577), the Barthel's function (r = 0.742), the MCT cognitive assessment (r = 0.651), and creatinine levels (r = 0.402). More than 50% of the sample presented at least one malnutrition parameter altered.
the MNA Scale presents lower sensitivity and specificity in these patients. Designing a nutritional assessment scale without subjective evaluations and only with objective parameters might improve its efficiency in institutionalized elderly patients with moderate-severe cognitive impairment.
鉴于此类患者中营养不良的高患病率,尤其是伴有认知障碍的患者,综合老年评估包括对营养状况的检查。用于筛查营养状况的量表包含一些痴呆老年患者难以回答的关于自我认知的问题。
研究微型营养评定法(MNA)量表在诊断为晚期认知障碍的阿尔茨海默病患者中检测营养不良的特异性、阳性预测值和敏感性。
设计了一项基于人群的描述性研究,样本为52名70岁以上、入住机构且患有中度至重度阿尔茨海默病的患者。针对美国营养学会(AIN)的营养不良参数,研究了MNA量表的敏感性、特异性和阳性预测值。
敏感性、特异性和阳性预测值分别为60%、94.7%和93.8%。MNA量表得分与Tinetti跌倒风险量表(r = 0.577)、Barthel功能量表(r = 0.742)、蒙特利尔认知评估量表(r = 0.651)以及肌酐水平(r = 0.402)之间存在显著相关性(p < 0.001)。超过50%的样本至少有一项营养不良参数异常。
MNA量表在这些患者中表现出较低的敏感性和特异性。设计一种仅含客观参数而无主观评估的营养评估量表,可能会提高其在中度至重度认知障碍的机构养老患者中的评估效率。