[一名中毒性表皮坏死松解症患者成功植入波士顿人工角膜]
[Successful Boston keratoprosthesis in a patient with Lyell's syndrome].
作者信息
Pinar-Sueiro S, Etxebarria-Ecenarro J, Gibelalde A, Closa-Clarià R, Martínez-Alday N
机构信息
Servicio de Oftalmología, Hospital de Cruces, Baracaldo, Vizcaya, España.
出版信息
Arch Soc Esp Oftalmol. 2009 Dec;84(12):635-40. doi: 10.4321/s0365-66912009001200009.
CASE REPORT
We present the case of a woman readmitted to our service to receive treatment for severe ophthalmic manifestations due to Lyell's syndrome. This intense affectation of the ocular surface along with limbal stem cell deficiency are grounds for treatment with Boston type 1 keratoprosthesis, which provided a stable and very satisfactory functional result.
DISCUSSION
As noted in this case report, the Boston Type 1 keratoprosthesis seems to be a viable option after multiple failed corneal grafts or in situations with a poor prognosis for primary penetrating keratoplasty because of limbal stem cell deficiency, such as Lyell's syndrome.
病例报告
我们介绍了一名女性患者，她因莱尔综合征导致严重眼部表现而再次入院接受治疗。眼表的这种严重病变以及角膜缘干细胞缺乏是使用波士顿1型人工角膜进行治疗的依据，该治疗取得了稳定且非常令人满意的功能结果。
讨论
如本病例报告所述，波士顿1型人工角膜似乎是在多次角膜移植失败后，或在因角膜缘干细胞缺乏（如莱尔综合征）而原发性穿透性角膜移植预后不佳的情况下的一种可行选择。
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