Basu Sayan, Sureka Shraddha, Shukla Rashmi, Sangwan Virender
Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
BMJ Case Rep. 2014 Mar 24;2014:bcr2013202756. doi: 10.1136/bcr-2013-202756.
Two young women with completely dry and keratinised eyes post-Stevens Johnson Syndrome (SJS) underwent unilateral oral mucous membrane grafts (MMGs) in preparation for modified osteo-odonto keratoprosthesis (MOOKP) implantation. In both cases, the mucosal graft was deemed to be too tight to accommodate the MOOKP implant. Instead of proceeding with MOOKP, the first patient underwent Auro Kpro (Boston type 1-based keratoprosthesis) implantation under the MMG, while the second patient underwent implantation of a modification of Auro Kpro with a longer optical stem (LVP Kpro) exposed through the MMG. Both patients maintained a visual acuity of 20/20, N6 at 15 months post-implantation. The first patient needed repeated mucosal trimming because of mucosal overgrowth; while in the second patient, mucosal overgrowth did not occur. This report highlights the innovative and successful use of Boston type 1-based keratoprosthesis (Auro Kpro) and its modification (LVP Kpro) in completely dry and keratinised post-SJS eyes.
两名患有史蒂文斯-约翰逊综合征（SJS）后眼睛完全干燥和角化的年轻女性接受了单侧口腔黏膜移植（MMG），为改良骨牙质角膜移植术（MOOKP）植入做准备。在这两个病例中，黏膜移植被认为太紧，无法容纳MOOKP植入物。第一名患者没有进行MOOKP手术，而是在MMG下植入了Auro Kpro（基于波士顿1型的角膜移植片），而第二名患者则植入了一种改良的Auro Kpro，其更长的光学柄通过MMG暴露在外。两名患者在植入后15个月时视力均保持在20/20，N6。第一名患者因黏膜过度生长需要反复进行黏膜修剪；而第二名患者未出现黏膜过度生长。本报告强调了基于波士顿1型的角膜移植片（Auro Kpro）及其改良版（LVP Kpro）在SJS后完全干燥和角化的眼睛中的创新和成功应用。
