Waldmann A, Dreckschmidt J, Pritzkuleit R, Katalinic A
Institut für Krebsepidemiologie e. V., Universität zu Lübeck, Ratzeburger Allee 160, Lübeck.
Gesundheitswesen. 2010 Oct;72(10):707-13. doi: 10.1055/s-0029-1242787. Epub 2010 Jan 4.
The OVIS study aims to outline and assess the health-care situation of patients with breast, prostate and skin cancer in Schleswig-Holstein. The used form contains questions regarding diagnosis, therapy, rehabilitation, post-operative health care, and quality of life and was administered approximately one year after primary therapy. The objective of this study (substudy of the OVIS study) is the evaluation of the test-retest reliability of this questionnaire in patients with breast cancer, who were questioned during and one year after primary therapy.
The study population was recruited during their ambulant chemotherapy and includes women with adjuvant and neoadjuvant treatment of their breast cancer. Patients with advanced metastasis were excluded. In total 56 patients, for whom medical records and both questionnaires were available, were included in this analysis. The test-retest reliability was measured using rates of absolute agreement and Cohen's kappa with a 95% confidence interval.
Of the 73 closed questions, 41% showed good and 52% showed moderate test-retest reliability. Test-retest reliability was high for questions regarding important moments (e.g., notification of breast cancer diagnosis), diagnostic (e.g., mammography) or therapeutic procedures (e.g., ablation mammae).
Although the time span between both questionings was one year, the acquired values of the test-retest reliability are consistent with those from comparable studies with shorter questioning intervals. The used questionnaire is a reliable instrument to determine the health care situation of women with breast cancer in Schleswig-Holstein.
OVIS研究旨在概述和评估石勒苏益格－荷尔斯泰因州乳腺癌、前列腺癌和皮肤癌患者的医疗状况。所使用的表格包含有关诊断、治疗、康复、术后医疗护理以及生活质量的问题，并且在初次治疗大约一年后进行填写。本研究（OVIS研究的子研究）的目的是评估该问卷在乳腺癌患者中的重测信度，这些患者在初次治疗期间及治疗后一年接受了询问。
研究人群是在其门诊化疗期间招募的，包括接受乳腺癌辅助和新辅助治疗的女性。排除有晚期转移的患者。共有56名患者纳入本分析，这些患者有病历记录且两份问卷均可用。使用绝对一致率和科恩kappa系数及95%置信区间来测量重测信度。
在73个封闭式问题中，41%显示出良好的重测信度，52%显示出中等的重测信度。关于重要时刻（如乳腺癌诊断通知）、诊断（如乳房X线摄影）或治疗程序（如乳房切除术）的问题，重测信度较高。
尽管两次询问之间的时间跨度为一年，但所获得的重测信度值与询问间隔较短的类似研究结果一致。所使用的问卷是确定石勒苏益格－荷尔斯泰因州乳腺癌女性医疗状况的可靠工具。
