Samedi Von, White Sherrie, Zimarowski Mary Jane, Harris Anna, Saffitz Jeffrey, Wang Helen H
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts 02215-5400, USA.
Diagn Cytopathol. 2010 Sep;38(9):675-81. doi: 10.1002/dc.21300.
Malignant peritoneal mesothelioma is uncommon but rapidly fatal with a median survival of less than 1 year. The diagnosis of this entity is often delayed because of the nonspecific presenting symptoms and nonspecific cytological features of the mesothelial cells in the peritoneal fluids. A 72-year-old man who had no known history of exposure to asbestos and had longstanding refractory ascites thought to be secondary to alcoholic cirrhosis was found to have widespread metastatic malignant mesothelioma involving the lung, liver, pancreas, peritoneal, and pelvic wall, skin and subcutaneous tissue.
恶性腹膜间皮瘤并不常见,但进展迅速,中位生存期不到1年。由于腹膜液中存在非特异性的临床表现和间皮细胞的非特异性细胞学特征,该疾病的诊断往往会延迟。一名72岁男性,无石棉接触史,长期患有难治性腹水,曾被认为继发于酒精性肝硬化,结果发现患有广泛转移的恶性间皮瘤,累及肺、肝、胰腺、腹膜和盆腔壁、皮肤及皮下组织。