Janssen Paul G H, Boomsma Louwrens J, Buis Pieter A J, Collette Corinne, Boukes Froukje S, Goudswaard A N Lex
Nederlands Huisartsen Genootschap, afd. Richtlijnontwikkeling en Wetenschap, Utrecht, The Netherlands.
Ned Tijdschr Geneeskd. 2009;153:A517.
A persistent infection with human papillomavirus (HPV) underlies all cases of cervical cancer. HPV testing is repeated 6 months after initial Pap smears 2 or 3a1. As vaccination against HPV is now included in the National Immunisation Programme of the Netherlands, yearly cervical cancer morbidity and mortality rates are expected to be cut by half. After vaccination against HPV, women still need to participate in the cervical cancer screening programme. Breastfeeding is no longer a contraindication for making Pap smears, provided that breastfeeding is indicated on the cytology application form. Liquid-based cervical cytology is an equivalent to conventional cervical cytology and offers the possibility of testing for HPV. General practitioners are responsible for communicating results from the cervical cancer screening programme to the participating women.
人乳头瘤病毒（HPV）的持续感染是所有宫颈癌病例的根本原因。在初次巴氏涂片检查2或3a1后6个月重复进行HPV检测。由于荷兰国家免疫计划现已纳入HPV疫苗接种，预计宫颈癌的年发病率和死亡率将减半。接种HPV疫苗后，女性仍需参加宫颈癌筛查计划。如果细胞学申请表上注明正在母乳喂养，那么母乳喂养不再是进行巴氏涂片检查的禁忌证。液基宫颈细胞学检查等同于传统宫颈细胞学检查，并提供了检测HPV的可能性。全科医生负责将宫颈癌筛查计划的结果告知参与筛查的女性。
