Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
J Clin Rheumatol. 2010 Jan;16(1):3-6. doi: 10.1097/RHU.0b013e3181c3444c.
To study the clinical presentation of poststreptococcal reactive arthritis (PSRA) and its periarticular manifestation.
This is a retrospective study. The files of all patients diagnosed with PSRA between January 2004 and November 2007 were reviewed with a predetermined checklist. Patients were included if they met our study criteria for diagnosis of PSRA.
A total of 33 files were reviewed; 26 of these patients (14 female, 12 male, Arab and Asian, aged 11-41 years) met our agreed protocol for the diagnosis of PSRA. The ethnic backgrounds of the patients were as follows: 18 patients were from Arab origins and 8 patients were Asians. Twenty-one patients (80%) had asymmetric complaints, whereas 5 patients (20%) had symmetrical complaints. Two patients (7.6%) had monoarthritis, 8 patients (30.76%) had oligoarthritis, and 11 patients (42.3%) had polyarthritis. Five patients (19.23%) had only polytendonitis, tenosynovitis, and/or enthesitis. Nine patients (34.61%) had tendonitis, tenosynovitis, or enthesitis alone or with arthritis/arthralgia. The average elevation of antistreptolysin antibodies titer was 624.8 and the average sedimentation rate 44 mm/H. The response to nonsteroidal antiinflammatory drugs was generally good (84.6%), being poor in only 4 patients (15.38%) who required treatment with corticosteroids. Prophylactic penicillin was given to 15 patients (57%). No patient had carditis on presentation or follow-up.
It is concluded that polytendonitis, tenosynovitis, and enthesitis are common presentations in PSRA and could be the only manifestation of poststreptococcal infection.
研究链球菌后反应性关节炎(PSRA)的临床特征及其关节外表现。
这是一项回顾性研究。我们对 2004 年 1 月至 2007 年 11 月期间所有诊断为 PSRA 的患者的病历进行了审查,并使用预定的检查表进行评估。如果患者符合我们 PSRA 诊断标准,我们就将其纳入研究。
共审查了 33 份病历,其中 26 份(14 名女性,12 名男性,阿拉伯人和亚洲人,年龄 11-41 岁)符合我们诊断 PSRA 的协议。患者的种族背景如下:18 名患者来自阿拉伯裔,8 名患者来自亚洲裔。21 名患者(80%)有不对称性症状,5 名患者(20%)有对称性症状。2 名患者(7.6%)为单关节炎,8 名患者(30.76%)为少关节炎,11 名患者(42.3%)为多关节炎。5 名患者(19.23%)仅有多发肌腱炎、腱鞘炎和/或附着点炎。9 名患者(34.61%)仅有肌腱炎、腱鞘炎或附着点炎,或伴有关节炎/关节痛。15 名患者(57%)接受了预防性青霉素治疗。抗链球菌溶血素“O”抗体滴度平均升高 624.8,平均沉降率 44mm/h。非甾体抗炎药的反应通常较好(84.6%),仅 4 名患者(15.38%)反应较差,需要皮质类固醇治疗。
多肌腱炎、腱鞘炎和附着点炎是 PSRA 的常见表现,可能是链球菌感染后的唯一表现。