University of Lausanne, Lausanne, Switzerland.
Obes Surg. 2010 Mar;20(3):326-31. doi: 10.1007/s11695-009-0055-9. Epub 2010 Jan 6.
Screening for obstructive sleep apnea (OSA) is recommended as part of the preoperative assessment of obese patients scheduled for bariatric surgery. The objective of this study was to compare the sensitivity of oximetry alone versus portable polygraphy in the preoperative screening for OSA.
Polygraphy (type III portable monitor) and oximetry data recorded as part of the preoperative assessment before bariatric surgery from 68 consecutive patients were reviewed. We compared the sensitivity of 3% or 4% desaturation index (oximetry alone) with the apnea-hypopnea index (AHI; polygraphy) to diagnose OSA and classify the patients as normal (<10 events per hour), mild to moderate (10-30 events per hour), or severe (>30 events per hour).
Using AHI, the prevalence of OSA (AHI > 10 per hour) was 57.4%: 16.2% of the patients were classified as severe, 41.2% as mild to moderate, and 42.6% as normal. Using 3% desaturation index, 22.1% were classified as severe, 47.1% as mild to moderate, and 30.9% as normal. With 4% desaturation index, 17.6% were classified as severe, 32.4% as mild, and 50% as normal. Overall, 3% desaturation index compared to AHI yielded a 95% negative predictive value to rule out OSA (AHI > 10 per hour) and a 100% sensitivity (0.73 positive predictive value) to detect severe OSA (AHI > 30 per hour).
Using oximetry with 3% desaturation index as a screening tool for OSA could allow us to rule out significant OSA in almost a third of the patients and to detect patients with severe OSA. This cheap and widely available technique could accelerate preoperative work-up of these patients.
肥胖患者在接受减重手术前,建议对其进行阻塞性睡眠呼吸暂停(OSA)筛查。本研究旨在比较单独血氧饱和度监测与便携式多导睡眠监测仪(polygraphy)在术前筛查 OSA 中的敏感性。
对 68 例连续患者在接受减重手术前的多导睡眠监测仪(type III 便携式监测仪)和血氧饱和度监测数据进行回顾性分析。我们比较了 3%或 4%的血氧饱和度下降指数(单独使用血氧饱和度监测)与呼吸暂停低通气指数(AHI;多导睡眠监测仪)的敏感性,以诊断 OSA,并将患者分类为正常(<10 次/小时)、轻度至中度(10-30 次/小时)或重度(>30 次/小时)。
根据 AHI,OSA 的患病率(AHI > 10 次/小时)为 57.4%:16.2%的患者被归类为重度,41.2%为轻度至中度,42.6%为正常。使用 3%的血氧饱和度下降指数,22.1%的患者被归类为重度,47.1%为轻度至中度,30.9%为正常。使用 4%的血氧饱和度下降指数,17.6%的患者被归类为重度,32.4%为轻度,50%为正常。总体而言,3%的血氧饱和度下降指数对 AHI 的阴性预测值为 95%,可排除 95%的 OSA(AHI > 10 次/小时),阳性预测值为 100%,可检测到 100%的重度 OSA(AHI > 30 次/小时)。
使用血氧饱和度监测仪,以 3%的血氧饱和度下降指数作为 OSA 的筛查工具,可排除近三分之一患者存在显著的 OSA,并可检测到严重的 OSA 患者。这种便宜且广泛应用的技术可以加速这些患者的术前检查。