East Carolina University Brody School of Medicine, Greenville, NC, USA.
Pediatr Blood Cancer. 2010 May;54(5):770-2. doi: 10.1002/pbc.22432.
Thromboembolism is a well-known complication of cancer including acute myeloid leukemia (AML) especially in patients with high myeloblast counts. However, spontaneous vaso-occlusion in the main arteries is very rare especially in patients with low blast counts and no pre existing vasculopathy. We report the case of a 3-year-old male with refractory AML who developed spontaneous bilateral internal carotid artery occlusion with diffuse cerebral infarcts. Strokes are rarely secondary to spontaneous carotid artery thrombosis and few cases have been reported in the literature.
血栓栓塞是癌症的一种已知并发症，包括急性髓系白血病（AML），特别是在高髓母细胞计数的患者中。然而，大血管的自发性血管阻塞非常罕见，特别是在低原始细胞计数且无预先存在的血管病变的患者中。我们报告了一例 3 岁男性难治性 AML 患者，其发生双侧颈内动脉自发性闭塞伴弥漫性脑梗死。中风很少继发于自发性颈动脉血栓形成，文献中报道的病例很少。
