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[憩室病的外科治疗现状]

[The current view of surgical treatment of diverticular disease].

作者信息

Zonca P, Jacobi C A, Meyer G P

机构信息

Zentrum für Viszeral und Minimal Invasive Chirurgie, Wesseling, Köln am Rhein, Nordrhein-Westfalen, Nĕmecko.

出版信息

Rozhl Chir. 2009 Oct;88(10):568-76.

Abstract

AIM

The aim of our prospective dynamic cohort trial is the evaluation of indication for surgery for diverticular disease and the evaluation of morbidity and mortality.

MATERIAL AND METHOD

All patients operated for diverticular disease and its complications were involved in the study. The conservatively treated patients were not involved. 104 patients with diverticular disease and its complication were operated from August 2007 till July 2008.46 men and 58 women at average age of 63.9 (31-85) years were in this group. 78 patients were electively operated in noninflammatory stage of diverticular disease. 3 patients of them had colovesical or enterocolical fistulas. An elective laparoscopic colon sigmoid resection was performed by 74 patients and a laparoscopic left hemicolectomy was performed by 4 patients. An end-to-end stapled colorectal suture was performed by all patients. An excision of fistula from urinary bladder and a segment resection of small bowel were performed in the case of fistula presence. In connection with previously repeated diverticulitis attacks or after previous surgeries, adhesiolysis was performed by 23 patients. 26 patients were operated for acute complication of diverticular disease. 24 patients of this group were operated for acute diverticulitis and 2 patients for diverticular bleeding. 23 colon sigmoideum resections, 2 left hemicolectomies, and once ileocecal resection were performed. The primary bowel suture was performed by 20 patients and Hartmaruts operation was performed by 4 patients.

RESULTS

The indication for surgery follows the classification according to Hansen and Stock. The abdominal postoperative complications (wound infection, anastomotic leak, prolongated bowel atonia, and others) occurred by elective operated group in 9% and by acute operated group in 26.9%. The overall abdominal postoperative complications occurred in all the involved patients in 13.4%. The extraabdominal postoperative complications (urinary infection or retention, cardiopulmonary complications, trombosis/embolia, postoperative qualitative conscious disorder, renal insufficiency, and others) occurred by elective group in 19.6% and by acute operated group in 50%. Overall extraabdominal postoperative complications occurred in all involved patients in 26.90%. The mortality was 0%. The conversion rate in elective group was 3.8% (3 pts.). An anastomosis leak occurred once (1%) by elective operated patient. An acute reoperation with resection according to Hartmann was performed. A small bowel loop perforation by coincidental adhesiolysis occurred once. A small bowel defect was identified and sutured by early laparoscopic reoperation. The conversion rate in acute group was 23.1% (6 pts.). The colonoscopy was necessary on 3rd day by 1 patient after left hemicolectomy for splenic flexure bleeding. This examination revealed bleeding from diverticulum in hepatic flexure. An endoscopic treatment was performed. An abscess in small pelvis occurred by this patient (12th postoperative day) and open drainage was performed. There was no anastomosis leak in group with acutely operated patients.

CONCLUSION

The usage of standard classification is suitable for operation's indication for diverticular disease and its complications. It helps to determine the type and operation's strategy. The acute complicated diveticulitis has high morbidity and mortality. The early indication of selected patients with diverticular disease for elective colon sigmoideum resection protects against possible complication in the case of next attack of diverticulitis. It concerns the patients with recidivated uncomplicated and complicated forms of disease as well. The primary conservative treatment with percutaneous CT navigated drainage allows a postponed elective surgery. The primary resection with suture is better than the two stage surgery. The primary laparoscopic resection is safe procedure in almost all the cases. The primary suture can be safely performed in all elective cases for uncomplicated diverticulitis, chronic fistulas, obstruction, for primarily conservatively treated stages Hinchey I and II and possibly for all the selected patients with Hinchey III and IV stages with MPI lower as 21.

摘要

目的

我们这项前瞻性动态队列试验的目的是评估憩室病手术指征以及评估发病率和死亡率。

材料与方法

所有因憩室病及其并发症接受手术的患者均纳入本研究。未纳入保守治疗的患者。2007年8月至2008年7月,104例患有憩室病及其并发症的患者接受了手术。该组中有46名男性和58名女性,平均年龄63.9(31 - 85)岁。78例患者在憩室病非炎症期接受择期手术。其中3例患者有结肠膀胱瘘或肠结肠瘘。74例患者接受了择期腹腔镜结肠乙状结肠切除术,4例患者接受了腹腔镜左半结肠切除术。所有患者均进行了端端吻合器结直肠缝合。如有瘘存在,则进行膀胱瘘切除和小肠部分切除术。因既往反复发生憩室炎发作或既往手术后,23例患者进行了粘连松解术。26例患者因憩室病急性并发症接受手术。该组中24例患者因急性憩室炎接受手术,2例患者因憩室出血接受手术。进行了23例结肠乙状结肠切除术、2例左半结肠切除术和1例回盲部切除术。20例患者进行了一期肠缝合,4例患者进行了Hartmann手术。

结果

手术指征遵循Hansen和Stock的分类。择期手术组腹部术后并发症(伤口感染、吻合口漏、肠麻痹延长等)发生率为9%,急性手术组为26.9%。所有纳入患者的总体腹部术后并发症发生率为13.4%。择期手术组腹部外术后并发症(泌尿系统感染或潴留、心肺并发症、血栓形成/栓塞、术后定性意识障碍、肾功能不全等)发生率为19.6%,急性手术组为50%。所有纳入患者的总体腹部外术后并发症发生率为26.90%。死亡率为0%。择期手术组的中转率为3.8%(3例)。择期手术患者中发生1次吻合口漏(1%)。进行了1次根据Hartmann法切除的急性再次手术。粘连松解术时偶然发生1次小肠袢穿孔。通过早期腹腔镜再次手术发现并缝合了小肠缺损。急性手术组的中转率为23.1%(6例)。1例患者左半结肠切除术后第3天因脾曲出血需要进行结肠镜检查。该检查发现肝曲憩室出血。进行了内镜治疗。该患者(术后第12天)发生盆腔小脓肿并进行了开放引流。急性手术患者组未发生吻合口漏。

结论

使用标准分类适用于憩室病及其并发症的手术指征。它有助于确定手术类型和策略。急性复杂性憩室炎发病率和死亡率高。对选定的憩室病患者早期进行择期结肠乙状结肠切除术可预防下次憩室炎发作时可能出现的并发症。这也涉及复发性非复杂性和复杂性疾病形式的患者。经皮CT引导下引流的初始保守治疗允许推迟择期手术。一期切除缝合优于二期手术。一期腹腔镜切除在几乎所有情况下都是安全的手术。对于非复杂性憩室炎、慢性瘘、梗阻、初始保守治疗的Hinchey I和II期以及可能所有选定的MPI低于21的Hinchey III和IV期患者,一期缝合在所有择期病例中均可安全进行。

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