Department of Clinical Neurophysiology, Swiss Epilepsy Center, Zurich, Switzerland.
Neuroimage. 2010 Apr 1;50(2):742-52. doi: 10.1016/j.neuroimage.2009.12.078. Epub 2010 Jan 4.
Theories of rhetoric and architecture suggest that buildings designed to be high ranking according to the Western architectural decorum have more impact on the minds of their beholders than low-ranking buildings. Here, we used event-related potentials in a visual object categorization task to probe this assumption and to examine whether the hippocampus contributes to the processing of architectural ranking. We found that early negative potentials between 200 and 400 ms differentiated between high- and low-ranking buildings in healthy subjects and patients with temporal lobe epilepsy with and without hippocampal sclerosis. By contrast, late positive potentials between 400 and 600 ms were higher in amplitude to high-ranking buildings only in healthy subjects and TLE patients without but not in TLE patients with hippocampal sclerosis. These findings suggest that the differentiation between high- and low-ranking buildings entails both early visual object selection and late post-model selection processes and that the hippocampus proper contributes critically to this second stage of visual object categorization.
修辞学和建筑学理论表明，按照西方建筑礼节设计的高层建筑物比低层建筑物对其观赏者的心理影响更大。在这里，我们使用视觉物体分类任务中的事件相关电位来探测这一假设，并研究海马体是否有助于处理建筑等级。我们发现，在健康受试者和伴有或不伴有海马硬化的颞叶癫痫患者中，200 至 400 毫秒之间的早期负电位可以区分高层和低层建筑物。相比之下，在健康受试者和不伴有海马硬化的颞叶癫痫患者中，400 至 600 毫秒之间的晚期正电位对高层建筑物的振幅更高，但在伴有海马硬化的颞叶癫痫患者中则不然。这些发现表明，高层和低层建筑物之间的区分既需要早期的视觉物体选择，也需要后期的模型选择过程，而海马体本身对视觉物体分类的这第二个阶段至关重要。
