Vannucci Manila, Pezer Nico, Helmstaedter Christoph, Schaller Karl, Viggiano Maria Pia, Elger Christian E, Grunwald Thomas
Department of Epileptology, Bonn University Medical Center, Bonn, Germany.
Neuroreport. 2008 Jun 11;19(9):965-8. doi: 10.1097/WNR.0b013e328302c89c.
The medial temporal lobe participates not only in episodic memory, but also in visual object processing. Here we asked whether these processes are linked within the human hippocampus. To this end, we recorded field potentials directly from the hippocampus proper during a visual object decision task in temporal lobe epilepsy patients with either normal or below normal visual memory performance. Only in patients with normal visual memory, did the hippocampus proper differentiate reliably between real and nonsense objects, whereas neural responses to both kinds of objects were virtually the same in patients whose visual memory performance was reduced. These findings suggest that neural responses to visual objects within the hippocampus proper are directly linked to visual memory performance.
内侧颞叶不仅参与情景记忆，还参与视觉物体处理。在此，我们探讨了这些过程在人类海马体中是否存在关联。为此，我们在颞叶癫痫患者进行视觉物体决策任务期间，直接记录了海马体本身的场电位，这些患者的视觉记忆表现正常或低于正常水平。仅在视觉记忆正常的患者中，海马体本身能够可靠地区分真实物体和无意义物体，而在视觉记忆表现降低的患者中，对这两类物体的神经反应几乎相同。这些发现表明，海马体本身对视觉物体的神经反应与视觉记忆表现直接相关。
