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[支气管镜扩张技术及丝裂霉素-C局部应用治疗气管插管后狭窄——两例报告]

[Bronchoscopic dilation techniques and topical application of mitomycin-C in the treatment of tracheal stenosis post intubation - two case reports].

作者信息

Ferreira Susana, Nogueira Carla, Oliveira Ana, Neves Sofia, Almeida José, Moura e Sá João

出版信息

Rev Port Pneumol. 2010 Jan-Feb;16(1):149-56. doi: 10.1016/s0873-2159(15)30012-x.

Abstract

Tracheal stenosis follows any injury to the airway mucosa, such as ischaemic, traumatic and other injuries. The treatment of tracheal stenosis remains a challenging problem despite all the advances in endoscopic and surgical techniques. Scar formation and reestenosis are the main causes of treatment failure. The authors present two cases of successful treatment of a tracheal stenosis after tracheal injury from prolonged oro -tracheal intubation / tracheostomy following dilatation with rigid broncoscope and laser therapy, associated with topical application of mitomycin C as an adjuvant treatment.

摘要

气管狭窄继发于气道黏膜的任何损伤,如缺血性、创伤性及其他损伤。尽管内镜和外科技术取得了诸多进展,但气管狭窄的治疗仍然是一个具有挑战性的问题。瘢痕形成和再狭窄是治疗失败的主要原因。作者介绍了两例成功治疗气管损伤后气管狭窄的病例,损伤由长期经口气管插管/气管切开术所致,采用硬支气管镜扩张和激光治疗,并局部应用丝裂霉素C作为辅助治疗。

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