Institut National de la Santé et de la Recherche Médicale, ERI 20, Université Paris-Sud EA 4045, and Institut Gustave Roussy, Villejuif F-94805 France.
Int J Geriatr Psychiatry. 2010 Nov;25(11):1142-9. doi: 10.1002/gps.2447.
To evaluate the performance of a French version of the modified Telephone Interview for Cognitive Status (F-TICS-m) in identifying cognitive decline among elderly women.
All women aged 72-86 participating in the 'Etude Epidémiologique auprès de Femmes de l'Education Nationale' (E3N) cohort and living in or near Paris constituted the target population of the validation study. Volunteer women (n = 120) underwent both a 20-min telephone interview and a face-to-face neuropsychological examination at an interval of few days (median interval: 10 days). The telephone interview included F-TICS-m, as well as a recall of key elements of a short story, arithmetic/verbal problems and two verbal fluency tests. Neuropsychological examination consisted of a standardized battery of cognitive tests (including the Mini-Mental State Examination (MMSE), the Free and Cued Selective Reminding Test-FCSRT, Trailmaking tests A and B, the similarities subtest of the Wechsler Adult Intelligence Scale-III, etc.) the Instrumental Activities of Daily Living questionnaire, and the Geriatric Depression Scale. Neuropsychological examination led to classification of each subject as cognitively normal (n = 92) or impaired/demented (n = 28).
F-TICS-m showed satisfactory internal consistency (Cronbach's alpha = 0.69). It correlated linearly with MMSE (Pearson's r = 0.72). Concurrent validity against the gold-standard classification was satisfactory, with an area under the ROC curve (AUC) of 0.83. The combination of F-TICS-m and the other telephone tests had no additional effect on discrimination power in our sample (AUC = 0.81).
F-TICS-m is a valid instrument for assessing the overall cognitive status of French elderly women. Its validity in men and its reproducibility warrant further studies.
评估法语改良电话认知状态测试（F-TICS-m）在识别老年女性认知能力下降方面的性能。
所有年龄在 72-86 岁之间、参与“国民教育女性流行病学研究”（E3N）队列且居住在巴黎或附近的女性均为验证研究的目标人群。志愿者女性（n=120）在几天内（中位间隔 10 天）先后接受了 20 分钟的电话访谈和面对面的神经心理学检查。电话访谈包括 F-TICS-m 以及短篇故事关键元素的回忆、算术/言语问题和两项言语流畅性测试。神经心理学检查包括标准化认知测试（包括简易精神状态检查（MMSE）、自由和提示选择性回忆测试-FCSRT、追踪测试 A 和 B、韦氏成人智力量表-III 的相似性子测验等）、日常生活活动工具问卷和老年抑郁量表。神经心理学检查导致每位受试者被分类为认知正常（n=92）或认知障碍/痴呆（n=28）。
F-TICS-m 表现出令人满意的内部一致性（Cronbach's alpha=0.69）。它与 MMSE 呈线性相关（Pearson's r=0.72）。与金标准分类的同时效度令人满意，ROC 曲线下面积（AUC）为 0.83。在我们的样本中，F-TICS-m 与其他电话测试的组合对区分能力没有额外的影响（AUC=0.81）。
F-TICS-m 是一种评估法国老年女性整体认知状态的有效工具。其在男性中的有效性和可重复性需要进一步研究。
