Dedet J-P
Université Montpellier 1, CHU de Montpellier, Laboratoire de Parasitologie, Montpellier, France.
Parassitologia. 2008 Dec;50(3-4):221-5.
Edmond and Etienne Sergent, "the Sergent brothers", were both born in Algeria. They both studied medicine at the Algiers Medical School and then followed the Course of Microbiology of Emile Roux at the Institut Pasteur in Paris (1899-1900). From 1900, they were put in charge of a permanent mission aimed at antimalarial control in Algeria, which was supervised by the Institut Pasteur. The first campaign was carried out during the summer of 1902 at a station of the East Algerian Railway Company. The success of this mission lead to the creation of the Antimalaric Department of Algeria in 1904, which was directed by Etienne Sergent for the duration his life. This antimalarial programme was progressively extended to many other locations. The programme was optimized between 1927 and 1947, in the experimental field study of the Ouled Mendil Marsh, where global environmental measures and drainage lead to settlement of farms, the families of which did not suffered from malaria. At a time when neither insecticides nor synthetic antimalarial drug existed, antimalarial control measures that were developed tended to target human reservoirs and the mosquito vectors. The extension of the programme across the Algerian territory lead to a decrease of both malaria endemicity and extension of affected areas.
埃德蒙和艾蒂安·塞尔让（“塞尔让兄弟”）都出生于阿尔及利亚。他们都在阿尔及尔医学院学习医学，随后在巴黎巴斯德研究所参加了埃米尔·鲁的微生物学课程（1899 - 1900年）。从1900年起，他们负责一项由巴斯德研究所监督的、旨在控制阿尔及利亚疟疾的长期任务。第一次行动于1902年夏天在东阿尔及利亚铁路公司的一个站点展开。这项任务的成功促使1904年阿尔及利亚抗疟部门的成立，艾蒂安·塞尔让在其有生之年一直负责该部门。这个抗疟项目逐渐扩展到许多其他地区。1927年至1947年期间，在乌尔德·门迪尔沼泽的实验性实地研究中，该项目得到了优化，在那里，全面的环境措施和排水工程使得农场得以定居，农场主的家人也不再遭受疟疾之苦。在既没有杀虫剂也没有合成抗疟药物的时代，所制定的抗疟控制措施往往针对人类宿主和蚊子媒介。该项目在阿尔及利亚全境的推广导致了疟疾流行程度的降低以及受影响地区范围的缩小。
