Saumya Pal Swakshyar, Gopal Lingam, Khetan Vikas, Nagpal Amit, Sharma Tarun
Vision Research Foundation, Chennai, Tamil Nadu, India.
J Pediatr Ophthalmol Strabismus. 2010 Nov-Dec;47(6):349-55. doi: 10.3928/01913913-20091218-03. Epub 2009 Dec 23.
To elucidate characteristics of rhegmatogenous retinal detachment that developed in children who underwent treatment for retinoblastoma and to analyze the outcome following vitreoretinal surgery in such clinical settings.
This was a retrospective case series of 9 eyes of 9 patients who underwent vitreoretinal surgery for tumor control and retinal reattachment.
At the time of diagnosis of rhegmatogenous retinal detachment, retinoblastoma was regressed in 6 eyes (67%). The retinal detachment involved less than two quadrants in 7 eyes (78%) and was caused by an atrophic break in 7 eyes. Seven eyes underwent a non-drainage scleral buckling procedure. Three eyes underwent vitreous surgery; in 2 of these eyes, tumor excision along with retinectomy using melphalan infusion was performed and eventually silicone oil tamponade was used. Retinal reattachment was achieved in all eyes with eventual tumor control in 7 eyes. The median follow-up after retinal reattachment surgery was 24 months.
Rhegmatogenous retinal detachment in treated eyes with retinoblastoma is usually caused by an atrophic retinal break. Retinal detachment can be repaired successfully in most eyes.
阐明接受视网膜母细胞瘤治疗的儿童发生孔源性视网膜脱离的特征，并分析在此临床情况下玻璃体视网膜手术后的结果。
这是一项回顾性病例系列研究，纳入了9例患者的9只眼睛，这些患者接受了玻璃体视网膜手术以控制肿瘤和使视网膜复位。
在诊断孔源性视网膜脱离时，6只眼睛（67%）的视网膜母细胞瘤已消退。7只眼睛（78%）的视网膜脱离累及不到两个象限，7只眼睛是由萎缩性裂孔引起的。7只眼睛接受了非引流性巩膜扣带术。3只眼睛接受了玻璃体手术；其中2只眼睛进行了肿瘤切除并使用美法仑灌注进行视网膜切除术，最终使用硅油填充。所有眼睛均实现了视网膜复位，7只眼睛最终实现了肿瘤控制。视网膜复位手术后的中位随访时间为24个月。
接受治疗的视网膜母细胞瘤患者眼睛中的孔源性视网膜脱离通常由萎缩性视网膜裂孔引起。大多数眼睛的视网膜脱离可以成功修复。
