Department of Dermatology, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland.
Clin Exp Dermatol. 2009 Dec;34(8):e859-61. doi: 10.1111/j.1365-2230.2009.03615.x.
Subacute cutaneous lupus erythematosus (SCLE) is a recognised variant of lupus erythematosus (LE), which accounts for 10-15% of all cases of cutaneous LE, occurring most commonly in young to middle-aged white women. Diagnosis is based on the detection of anti-Ro/SS-A antibodies in the skin and serum, characteristic clinical and histological cutaneous involvement, and relatively mild systemic involvement. Several unusual variants of SCLE have been reported including erythrodermic SCLE, SCLE with vitiligo-like lesions, acral SCLE and bullous SCLE. Poikoilodermatous SCLE is a recognised but rare variant of SCLE. There are currently only two case reports, comprising five individual cases, in the literature. We present a case of SCLE in which the main clinical findings were an extensive photodistributed poikilodermatous rash and alopecia.
亚急性皮肤型红斑狼疮(SCLE)是红斑狼疮(LE)的一种公认变异型,占所有皮肤型 LE 的 10-15%,最常发生于中青年白人女性。诊断基于皮肤和血清中抗 Ro/SS-A 抗体的检测、特征性的临床和组织学皮肤受累以及相对较轻的全身受累。已报道了几种不常见的 SCLE 变异型,包括红皮病型 SCLE、SCLE 伴白癜风样皮损、肢端型 SCLE 和大疱型 SCLE。色素异常性 SCLE 是一种公认但罕见的 SCLE 变异型。目前文献中仅有两例病例报告,共包含五例个案。我们报告了一例 SCLE 病例,其主要临床发现为广泛分布的光感性色素异常性皮疹和脱发。