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早产儿视觉功能的早期评估:多早算早?

Early assessment of visual function in preterm infants: how early is early?

机构信息

Paediatric Neurology Unit, Catholic University, Rome, Italy.

出版信息

Early Hum Dev. 2010 Jan;86(1):29-33. doi: 10.1016/j.earlhumdev.2009.11.004. Epub 2010 Jan 6.

DOI:10.1016/j.earlhumdev.2009.11.004
PMID:20056358
Abstract

BACKGROUND

Several studies reported on various aspects of visual function at term age and in the first months after birth but less has been reported in preterm infants before they reach termequivalent age.

AIMS

To assess the suitability of a battery of tests of visual function for use in infants born at <33weeks gestation (GA) and assessed before 34weeks post-menstrual age (PMA); to evaluate the distribution of the findings according to GA, and to compare the data with those previously published on preterm infants assessed at 35weeks PMA.

STUDY DESIGN

Cross-sectional study.

SUBJECTS

Sixty-four preterm infants with a GA <33weeks were studied.

OUTCOME MEASURES

We used a battery of visual function tests previously validated at 35 and 40weeks PMA in low-risk preterm infants. All the infants in this current study underwent the same assessment before 34weeks PMA.

RESULTS

Before 31weeks PMA most infants could not be reliably assessed because of clinical instability, whilst after 31weeks PMA most infants could be assessed and they showed progressive maturation in their responses with PMA. Some items (spontaneous ocular motility, horizontal tracking, tracking a coloured stimulus, and ocular fixation) showed similar results at 32-33weeks PMA to those found in low-risk preterm at 35weeks PMA. Ocular movements to a target and arc tracking were the items with the most immature responses.

CONCLUSIONS

Our results provide further evidence that a structured assessment of visual function can be used in clinical routine and for research purposes in infants as young as 31weeks PMA.

摘要

背景

有几项研究报告了足月龄和出生后第一个月的视觉功能的各个方面,但早产儿在达到足月龄之前的相关研究则较少。

目的

评估一系列视觉功能测试在<33 孕周(GA)出生并在 34 周校正胎龄(PMA)之前评估的婴儿中的适用性;根据 GA 评估结果的分布,并将数据与之前在 35 周 PMA 评估的早产儿的数据进行比较。

研究设计

横断面研究。

受试者

64 名 GA<33 周的早产儿。

结果测量

我们使用了之前在低危早产儿中在 35 周和 40 周 PMA 验证过的视觉功能测试组合。本研究中的所有婴儿都在 34 周 PMA 之前接受了相同的评估。

结论

我们的结果进一步证明,结构化的视觉功能评估可以在临床常规中以及在 31 周 PMA 时的婴儿中用于研究目的。

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