HSR&D/RR&D Research Center of Excellence, James A. Haley Veterans Hospital, 8900 Grand Oak Circle, Tampa, FL 33637-1022, USA.
J Aging Health. 2010 Mar;22(2):219-41. doi: 10.1177/0898264309355981. Epub 2010 Jan 7.
Guided by a life-course approach to chronic disease, this study examined the ways in which childhood deprivation (low parental education and father's manual occupation) may be associated with coronary heart disease (CHD).
Multilevel modeling techniques and a nationally representative sample of Americans above age 50 from the Health and Retirement Study (HRS; N = 18,465) were used to examine childhood and CHD relationships over the course of 6 years (1998-2004).
Having a father with </=8 years of education was associated with 11% higher odds of CHD, accounting for demographic characteristics, adult socioeconomic status (SES; education, income, and wealth), CHD risks (diabetes, hypertension, cigarette smoking, and obesity), and other factors (childhood health, exercise, stroke, and marital status).
Policies and programs aimed at improving the conditions of poor children and their families may effectively reduce the prevalence of CHD in later life.
本研究以慢性病的生命历程方法为指导，探讨童年剥夺（父母受教育程度低和父亲从事体力劳动）与冠心病（CHD）之间的关系。
使用多层次建模技术和来自健康与退休研究（HRS）的超过 50 岁的美国全国代表性样本（N=18465），在 6 年（1998-2004 年）的时间内考察了童年和 CHD 之间的关系。
父亲受教育程度<=8 年与 CHD 的发生风险增加 11%相关，这一关联在控制了人口统计学特征、成人社会经济地位（教育、收入和财富）、CHD 风险（糖尿病、高血压、吸烟和肥胖）以及其他因素（儿童健康、运动、中风和婚姻状况）后依然存在。
旨在改善贫困儿童及其家庭状况的政策和项目可能会有效降低晚年 CHD 的发生率。
