氯法拉滨诱发一名难治性急性淋巴细胞白血病患儿出现毛细血管渗漏综合征。
Clofarabine-induced capillary leak syndrome in a child with refractory acute lymphoblastic leukemia.
作者信息
Baytan Birol, Ozdemir Ozlem, Gunes Adalet Meral, Dönmez Osman
机构信息
Departments of Pediatric Hematology, Uludag University, Bursa, Turkey.
出版信息
J Pediatr Hematol Oncol. 2010 Mar;32(2):144-6. doi: 10.1097/MPH.0b013e3181bf298b.
PMID:20057324
Abstract
Clofarabine has significant efficiency in children with relapsed or refractory leukemia. In previous pediatric trials, various adverse effects have been described. In this case, we report a child with refractory acute lymphoblastic leukemia who developed fatal capillary leak syndrome during clofarabine therapy.
摘要
氯法拉滨对复发或难治性白血病患儿有显著疗效。在以往的儿科试验中，已描述了各种不良反应。在此病例中，我们报告了一名难治性急性淋巴细胞白血病患儿，其在氯法拉滨治疗期间发生了致命的毛细血管渗漏综合征。
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