Horowitz M E, Neff J R, Kun L E
Pediatric Branch, National Cancer Institute, Bethesda, Maryland.
Pediatr Clin North Am. 1991 Apr;38(2):365-80. doi: 10.1016/s0031-3955(16)38082-8.
Significant strides in the treatment of Ewing's sarcoma, the second most common bone tumor of childhood, have resulted in cure for approximately 50% of patients. Successful therapy requires systemic chemotherapy for the eradication of microscopic or overt metastatic disease and surgery or irradiation therapy for control of the primary lesion. The article debates the controversy over the extent to which surgical resection should play a role in the local management of this disease.
尤因肉瘤是儿童第二常见的骨肿瘤，其治疗取得了重大进展，约50%的患者得以治愈。成功的治疗需要全身化疗以根除微小或明显的转移性疾病，以及手术或放射治疗以控制原发性病变。本文探讨了手术切除在该疾病局部治疗中应发挥何种作用的争议。
