Centro Regionale di Diagnosi e Follow-up dell' Ipotiroidismo Congenito, Cattedra di Pediatria, Università degli Studi Magna Graecia, Ospedale Pugliese, Catanzaro, Italy.
Ann Ist Super Sanita. 2009;45(4):443-6. doi: 10.1590/s0021-25712009000400015.
Neonatal screening of congenital hypothyroidism (CH), carried out on all newborns 3rd -5th day of life, has a very important priority because the incidence of this disease is the highest of all congenital diseases involving brain damage which can be preventable with early specific treatment. In recent years, the values of TSH that were considered pathological were modified and the TSH cut-off, the title of hormone to be taken as the limit of significance for determining a subject suffering from CH, has been progressively lowered. In Calabria the introduction of the new value of TSH cut-off on blood spot, has led to a considerable increase in the frequency of CH, particularly in the case of the thyroid in situ normal ultrasound and of the diagnosis of transitional forms of CH.
新生儿先天性甲状腺功能减退症（CH）筛查在所有新生儿出生后第 3-5 天进行，具有非常重要的优先级，因为该病的发病率是所有涉及脑损伤的先天性疾病中最高的，这种脑损伤可以通过早期的特异性治疗来预防。近年来，人们对 TSH 的病理值进行了修正，将 TSH 截止值作为判断 CH 患者的激素界限，该值逐渐降低。在卡拉布里亚，血斑 TSH 截止值的新值的引入，导致 CH 的频率显著增加，特别是在超声检查甲状腺原位正常和 CH 过渡形式的诊断的情况下。
